Regenerative Biological Effects of Platelet-Rich Plasma (PRP) Therapy in Orthopaedic Sports Medicine

Onur ORAL^1, , George NOMİKOS² and Nikitas NOMIKOS^{3, 4}

¹Ege University, Faculty of Sports Sciences, Izmir, Turkey

²Chios Hospital, Department of Orthopaedic Surgery, Chios, Greece

³School of Physical Education & Sport Science, National & Kapodistrian University of Athens

⁴Medical School, National & Kapodistrian University of Athens

Cite this paper

Onur ORAL, George NOMİKOS and Nikitas NOMIKOS. Regenerative Biological Effects of Platelet-Rich Plasma (PRP) Therapy in Orthopaedic Sports Medicine. American Journal of Sports Science and Medicine. 2020; 8(1):20-22. doi: 10.12691/AJSSM-8-1-4

Abstract

Sports injuries may lead to severe consequences for athletes. Many athletes suffer from injuries of skeletal muscle. While these injuries may be minor, they may be quite serious [1]. An athlete needs to train on a regular basis. An injury causes her/his time to be wasted. Similarly, if the athlete is a member of a certain team, the injury affects multiple people. Platelet-rich plasma (PRP) is a quite promising technique with significant potentials. PRP is an autologous blood product used in terms of sports medicine to treat acute and chronic tendon, ligament, and muscle injuries in over 86,000 athletes in the United States on annual basis [2]. PRP is a quite promising technique with significant potentials. It is expected to accelerate the healing process of tendon and ligament related injuries. This is particularly advantageous for athletes [3].

Keywords

plasma, therapy, sports medicine, orthopaedic

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Longo UG, Loppini M, Berton A, Spiezia F, Maffulli N, Denaro V. (2012). Tissue Engineered Strategies for Skeletal Muscle Injury. Stem Cells International. 2012:175038.
[2]	Wasterlain AS, Braun HJ, Harris AH, Kim HJ, Dragoo JL. (2013). The Systemic Effects of Platelet-Rich Plasma Injection. Am J Sports Med. 41(1):186-93.
[3]	Taylor DW, Petrera M, Hendry M, Theodoropoulos JS. (2011). MD A Systematic Review of the Use of Platelet-Rich Plasma in Sports Medicine as a New Treatment for Tendon and Ligament Injuries. Clin J Sport Med.; 21(4): 344-352.
[4]	Beiner JM and Jokl P. (2001). Muscle contusion injuries: current treatment options.The Journal of the American Academy of Orthopaedic Surgeons, vol. 9, no. 4, pp. 227-237.
[5]	Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA. (2009). Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med. 37(11): 2259-2272.
[6]	Anitua E, Sanchez M, Nurden AT, et al. (2006). Autologous fibrin matrices: a potential source of biological mediators that modulate tendon cell activities. J Biomed Mater Res A. 77(2): 285-293.
[7]	Eppley BL, Woodell JE, Higgins J. (2004) Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. PlastReconstr Surg. 114(6):1502-1508.
[8]	Rodrigues SV, Acharya AB, Thakur SL (2012) Platelet-rich plasma. A review. N Y State Dent J.; 78(1): 26-30.
[9]	Marx RE (2004) Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg.; 62: 489-496.
[10]	Creaney L, Hamilton B. (2008). Growth factor delivery methods in the management of sports injuries: the state of play. Br J Sports Med. 42(5): 314-320.
[11]	Sanchez AR, Sheridan PJ, Kupp LI. (2003). Is platelet-rich plasma the perfect enhancement factor? a current review. Int J Oral Maxillofac Implants. 18:93-103.
[12]	Tozum TF, Demiralp B (2003). Platelet-rich plasma: a promising innovation in dentistry. J canadian Dent assoc. 69:664- 669.
[13]	Marx RE. (2001). Platelet-Rich Plasma (PRP): What Is PRP and What Is Not PRP? Implant Dent. 10(4): 225-8.
[14]	Mishra A, Pavelko T. (2006) Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med.; 34: 1774-1778.
[15]	Peerbooms JC, Sluimer J, Bruijn DJ, et al. (2010). Platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med.; 38: 255-262.
[16]	deVos RJ, Weir A, van Schie HT, et al. (2010) Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA.; 303: 144-149.
[17]	Gaweda K, Tarczynska M, Krzyzanowski W. (2010). Treatment of Achilles tendinopathy with platelet-rich plasma. Int J Sports Med.; 31: 577-583.
[18]	Orrego M, Larrain C, Rosales J, et al. (2008). Effects of platelet concentrate and a bone plug on the healing of hamstring tendons in a bone tunnel. Arthroscopy; 24: 1373-1380.
[19]	Silva A, Sampaio R (2009). Anatomic ACL reconstruction: does the platelet-rich plasma accelerate tendon healing? Knee Surg Sports Traumatol Arthrosc.; 17: 676-682.